Atellani House is one of the few fifteenth-century buildings left in Milan. It was a gift from Duke Ludovico il Moro to one of his supporters. The palace became famous for the sumptuous parties that were held there, to which the major personalities of the Sforza court took part.

Part of the inside garden was once a section of the vineyard, which was recognized to be donated by the Duke of Milan to Leonardo da Vinci as a reward for the painting of the “Last Supper” in the refectory of the convent of Santa Maria delle Grazie.